Lu Lab Lu Lei

Research

To view my recent research, please look to my google scholar.

做点有趣的东西发表吧 😁

有点乱,代码好像出问题了,以后有空再弄吧 😔

Highlighted

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All

2024

SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex
SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex
Lee Schnaider, Sophia Tan, Pratik R. Singh, Floriana Capuano, Alistair J. Scott, …, Lei Lu, Hyunjun Yang, E. Jayne Wallace, Hyunil Jo, William F. DeGrado
Journal of the American Chemical Society  ·  27 Aug 2024  ·  doi:10.1021/jacs.4c07920
De novo design of drug-binding proteins with predictable binding energy and specificity
De novo design of drug-binding proteins with predictable binding energy and specificity
Lei Lu, Xuxu Gou, Sophia K. Tan, Samuel I. Mann, Hyunjun Yang, …, Yibing Wu, Morgan E. Diolaiti, Alan Ashworth, Nicholas F. Polizzi, William F. DeGrado
Science  ·  05 Apr 2024  ·  doi:10.1126/science.adl5364

2021

Mesh Fragmentation Improves Dissociation Efficiency in Top-down Proteomics
Mesh Fragmentation Improves Dissociation Efficiency in Top-down Proteomics
Lei Lu, Mark Scalf, Michael R. Shortreed, Lloyd M. Smith
Journal of the American Society for Mass Spectrometry  ·  23 Mar 2021  ·  doi:10.1021/jasms.0c00462
Binary Classifier for Computing Posterior Error Probabilities in MetaMorpheus
Binary Classifier for Computing Posterior Error Probabilities in MetaMorpheus
Michael R. Shortreed, Robert J. Millikin, Lei Liu, Zach Rolfs, Rachel M. Miller, Leah V. Schaffer, Brian L. Frey, Lloyd M. Smith
Journal of Proteome Research  ·  08 Mar 2021  ·  doi:10.1021/acs.jproteome.0c00838

2020

O-Pair Search with MetaMorpheus for O-glycopeptide characterization
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
Lei Lu, Nicholas M. Riley, Michael R. Shortreed, Carolyn R. Bertozzi, Lloyd M. Smith
Nature Methods  ·  01 Nov 2020  ·  https://doi.org/10.1038/s41592-020-00985-5
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
Lei Lu, Nicholas M. Riley, Michael R. Shortreed, Carolyn R. Bertozzi, Lloyd M. Smith
Nature Methods  ·  26 Oct 2020  ·  doi:10.1038/s41592-020-00985-5
Spritz: A Proteogenomic Database Engine
Spritz: A Proteogenomic Database Engine
Anthony J. Cesnik, Rachel M. Miller, Khairina Ibrahim, Lei Lu, Robert J. Millikin, Michael R. Shortreed, Brian L. Frey, Lloyd M. Smith
Journal of Proteome Research  ·  23 Sep 2020  ·  doi:10.1021/acs.jproteome.0c00407
O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
Lei Lu, Nicholas M. Riley, Michael R. Shortreed, Carolyn R. Bertozzi, Lloyd M. Smith
Cold Spring Harbor Laboratory  ·  20 May 2020  ·  doi:10.1101/2020.05.18.102327

2019

HOTMAQ: A Multiplexed Absolute Quantification Method for Targeted Proteomics
HOTMAQ: A Multiplexed Absolute Quantification Method for Targeted Proteomics
Xiaofang Zhong, Qinying Yu, Fengfei Ma, Dustin C. Frost, Lei Lu, Zhengwei Chen, Henrik Zetterberg, Cynthia Carlsson, Ozioma Okonkwo, Lingjun Li
Analytical Chemistry  ·  04 Jan 2019  ·  doi:10.1021/acs.analchem.8b04580

2018

Identification of MS-Cleavable and Noncleavable Chemically Cross-Linked Peptides with MetaMorpheus
Identification of MS-Cleavable and Noncleavable Chemically Cross-Linked Peptides with MetaMorpheus
Lei Lu, Robert J. Millikin, Stefan K. Solntsev, Zach Rolfs, Mark Scalf, Michael R. Shortreed, Lloyd M. Smith
Journal of Proteome Research  ·  25 May 2018  ·  doi:10.1021/acs.jproteome.8b00141

De novo design of drug-binding proteins with predictable binding energy and specificity
De novo design of drug-binding proteins with predictable binding energy and specificity
Lei Lu, Xuxu Gou, Sophia K. Tan, Samuel I. Mann, Hyunjun Yang, …, Yibing Wu, Morgan E. Diolaiti, Alan Ashworth, Nicholas F. Polizzi, William F. DeGrado
Science  ·  [no date info]  ·  10.1126/science.adl5364
Drug binding protein design.